Biochemistry of Anaerobic Microbes Lab

Working at the intersection of Chemistry and Microbiology

Our approach

We employs an interdisciplinary approach to study processes that significantly impact the global carbon cycle, alternative energy sources, and biomedical applications. We work at the intersection of chemistry, anaerobic microbiology, and biophysics, exploring processes essential to these fields. A primary focus of our research is to develop a molecular understanding of the proteins involved in electron transport, energy conservation, and stress response in anaerobic microbes. The questions we investigate are addressed using a variety of methods, including molecular biology, genetics, protein expression and purification, spectroscopy, transient-state kinetics, and structural biology.  

Lab news

Fall 2025

  • Postdoctoral opportunity:

    We are seeking a highly motivated individual for a postdoctoral research position in the field of Biochemistry of Metalloproteins / Bioinorganic Chemistry. The project involves investigating the mechanisms of electron-bifurcating heterodisulfide reductases and the reaction mechanisms of ferredoxin disulfide reductases through pre-steady-state and steady-state kinetics, as well as spectroscopic techniques (EPR, Mossbauer, and IR), and biophysical methods (SAXS, SANS, Cryo-EM, and X-ray crystallography). Candidates with experience in metalloproteins and proficiency in operating the Stopped-Flow technique and analyzing results are required. While experience with spectroscopic methods, biophysical techniques, and anaerobic microbes is desirable, it is not mandatory. The position offers training opportunities, including teaching selected lectures each year in biochemistry and microbial physiology, as well as assisting in training undergraduate and graduate students. Interested candidates should contact Dr. Divya Prakash at divya.prakash@siu.edu with a curriculum vitae and a cover letter explaining why they are the best fit for the group. Please visit the lab's website for details about the work: https://www.divyalab.com/

    .

    Requirements
    Qualifications: A Ph.D. degree in Chemistry, Biochemistry, or a closely related discipline is required. Candidates should demonstrate a strong dedication to research and possess a passion for mentoring students.

    Spring 2024

  • The lab received ARPA-E DOE funding ($1.1M) for hydrogen harvesting in collaboration with Dr. Shimin Liu at Penn State and Dr. Satya Harpilani at SIUC.

Fall 2023

  • Two seed grants have been awarded to the lab:

    1. Soybean Research Grant

    2. Advanced Research Institute.

    Spring 2023

  •  A first grant of $158 K was awarded to the lab.

    Fall 2022

  • The lab welcomes doctorate students Mahmudun Noby, Cat Nimmno and Neelima Bhatt!

  • The lab welcomes first undergraduate Hannah Kruse!

 

Our lab/office is conveniently located at SIU (Southern Illinois University).

School of Chemical and Biomolecular Sciences

Office: Neckers 325

Lab: Neckers 309/307

1245 Lincoln Drive

Carbondale, Illinois,

62901. USA